Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253224 | 0.82 | LMNA (0.49) | GRIA4LMNAMAPTNR1H4TSHR | |
| SCHEMBL6968539 | 0.82 | TAAR1 (0.59) | GRIA4LMNASLC6A2SLC6A3NR1H4 | |
| SCHEMBL26205758 | 0.82 | PDE2A (0.49) | LMNAESR1CYP1A2PGRCHRM2 | |
| SCHEMBL23058763 | 0.82 | PDE2A (0.49) | LMNAESR1CYP1A2PGRCHRM2 | |
| SCHEMBL6948298 | 0.79 | LMNA (0.43) | GRIA4LMNAMAPTNR1H4TSHR | |
| SCHEMBL6940717 | 0.79 | LMNA (0.43) | GRIA4LMNAMAPTNR1H4TSHR | |
| SCHEMBL548052 | 0.78 | GRIA4 (0.53) | GRIA4LMNACYP2C9ALOX15GAA | |
| SCHEMBL18092983 | 0.78 | GRIA4 (0.53) | GRIA4LMNACYP2C9ALOX15GAA | |
| SCHEMBL18387217 | 0.78 | TSHR (0.46) | GRIA4LMNANR1H4TSHRTP53 | |
| SCHEMBL15435180 | 0.77 | GRIA4 (0.42) | GRIA4LMNAESR1CYP1A2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |