Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948449 | 0.82 | GRIA4 (0.45) | TAAR1SLC6A2SLC6A3GRIA4NR1H4 | |
| SCHEMBL18253224 | 0.80 | LMNA (0.49) | GRIA4NR1H4LMNAEPHX1TSHR | |
| SCHEMBL6982075 | 0.79 | TAAR1 (0.56) | TAAR1GRIA4NR1H4LMNAEPHX1 | |
| SCHEMBL5878391 | 0.79 | TAAR1 (0.56) | TAAR1GRIA4NR1H4LMNAEPHX1 | |
| SCHEMBL6940717 | 0.77 | LMNA (0.43) | GRIA4NR1H4LMNAEPHX1TSHR | |
| SCHEMBL6948298 | 0.77 | LMNA (0.43) | GRIA4NR1H4LMNAEPHX1TSHR | |
| SCHEMBL8011990 | 0.77 | TAAR1 (0.65) | TAAR1SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL18387217 | 0.76 | TSHR (0.46) | GRIA4NR1H4LMNAEPHX1TSHR | |
| SCHEMBL11660622 | 0.75 | TSHR (0.41) | GRIA4LMNATSHRTP53TYR | |
| SCHEMBL17892070 | 0.75 | TAAR1 (0.63) | TAAR1SLC6A2SLC6A4SLC6A3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021411-B1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6326386-B1 | ANTICOAGULANT | GLAXO GROUP LIMITED (GB) | 2001-12-04 | — | — | US | disclosed |