SCHEMBL6948490

SCHEMBL6948490

[CH2]C(C)=CCCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
GRIK1 P39086 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
GPR52 Q9Y2T5 5/20 0.42
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
TAAR1 Q96RJ0 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ATM Q13315 1/20 0.39
KEAP1 Q14145 1/20 0.39
TRPV1 Q8NER1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105976 0.83 TRPV1 (0.51) ALDH1A1GRIK1TDP1GPR52HPGD
SCHEMBL11517480 0.79 ALDH1A1 (0.45) ALDH1A1GRIK1TDP1GPR52HPGD
SCHEMBL7168307 0.78 TDP1 (0.50) ALDH1A1GRIK1TDP1GPR52HPGD
SCHEMBL108850 0.78 ALDH1A1 (0.44) ALDH1A1GRIK1TDP1GPR52TRPV1
SCHEMBL108851 0.78 ALDH1A1 (0.44) ALDH1A1GRIK1TDP1GPR52TRPV1
SCHEMBL29105881 0.78 ALDH1A1 (0.53) ALDH1A1GRIK1TDP1GPR52KEAP1
SCHEMBL24095822 0.76 GRIK1 (0.45) ALDH1A1GRIK1TDP1GPR52SMN1; SMN2
SCHEMBL5599478 0.76 ALDH1A1 (0.47) ALDH1A1GRIK1TDP1GPR52HPGD
SCHEMBL14308631 0.76 ALDH1A1 (0.47) ALDH1A1GRIK1TDP1GPR52HPGD
SCHEMBL197322 0.76 GRIK1 (0.53) ALDH1A1GRIK1GPR52HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337536-A1 CATIONIC GROUP-3 CATALYST SYSTEM ExxonMobil Chemical Patents Inc. (US) 2003-08-27 EP disclosed
WO-2002032909-A1 CATIONIC GROUP-3 CATALYST SYSTEM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-04-25 WO disclosed