Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946841 | 0.83 | HTR1A (0.47) | HTR1AHTR7DRD3DRD2 | |
| SCHEMBL13315677 | 0.81 | CASP3 (0.39) | ACHEKMT2AALDH1A1CASP3 | |
| SCHEMBL27679483 | 0.81 | CA12 (0.45) | ACHEKMT2AALDH1A1CASP3 | |
| SCHEMBL13315610 | 0.79 | CASP3 (0.45) | KMT2ANPC1ALDH1A1RAB9ACASP3 | |
| SCHEMBL3127337 | 0.76 | PDK4 (0.46) | KMT2A | |
| SCHEMBL13797923 | 0.76 | CASP3 (0.47) | KMT2AALDH1A1CASP3HTR1A | |
| SCHEMBL6947836 | 0.76 | CASP3 (0.52) | CASP3DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL3135589 | 0.74 | CASP3 (0.46) | KMT2AALDH1A1CASP3HTR1A | |
| SCHEMBL13797913 | 0.74 | CASP3 (0.40) | ACHEKMT2ANPC1ALDH1A1RAB9A | |
| SCHEMBL13797919 | 0.74 | CASP3 (0.40) | ACHEKMT2ANPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |