SCHEMBL6948515

SCHEMBL6948515

Cl[SiH](Cl)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
TSHR P16473 3/20 0.45
CA4 P22748 1/20 0.41
KCNA3 P22001 1/20 0.38
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TAAR1 Q96RJ0 1/20 0.33
RECQL P46063 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SRC P12931 1/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5031062 0.78 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL11415511 0.76 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL275159 0.75 LTA4H (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL27882572 0.71 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL310041 0.71 CA4 (0.48) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL6840036 0.71 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL705308 0.71 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL7694976 0.71 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2354326 0.71 CA4 (0.48) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2231315 0.70 LTA4H (0.39) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2963074-B1 CYCLOPENTENE RING-OPENING COPOLYMER, METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION ZEON CORP (JP) 2021-04-14 EP disclosed
US-10435497-B2 Cyclopentene ring-opening copolymer, method for producing same, and rubber composition ZEON CORPORATION (JP) 2019-10-08 US disclosed
US-10246525-B2 Process for producing conjugated diene polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-04-02 US disclosed
EP-3023439-B1 METHOD FOR PRODUCING POLYMER ASAHI CHEMICAL IND (JP) 2018-02-07 EP disclosed
US-20170260301-A1 Process for Producing Conjugated Diene Polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
EP-3196223-A1 CYCLOOLEFIN-BASED RUBBER AND PROCESS FOR PRODUCING SAME, RUBBER COMPOSITION, CROSSLINKED RUBBER OBJECT, AND TIRE Zeon Corporation (JP) 2017-07-26 EP disclosed
EP-3192634-A1 METHOD FOR PRODUCING CONJUGATED DIENE POLYMER Asahi Kasei Kabushiki Kaisha (JP) 2017-07-19 EP disclosed
EP-3023439-A1 POLYMER MANUFACTURING METHOD Asahi Kasei Chemicals Corporation (JP) 2016-05-25 EP disclosed
US-20160002382-A1 CYCLOPENTENE RING-OPENING COPOLYMER, METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION ZEON CORPORATION (JP) 2016-01-07 US disclosed
EP-2963074-A1 CYCLOPENTENE RING-OPENING COPOLYMER, METHOD FOR PRODUCING SAME, AND RUBBER COMPOSITION Zeon Corporation (JP) 2016-01-06 EP disclosed
CN-102816359-A Method of producing a tire composition having improved silica reinforcement BRIDGESTONE CORP 2012-12-12 CN disclosed
CN-101668780-B Method for producing modified conjugated diene polymer, modified conjugated diene polymer, and rubber composition JSR CORP 2012-11-28 CN disclosed
CN-101220102-B Amine-containing alkoxysilyl functionalized polymers BRIDGESTONE CORP 2012-10-31 CN disclosed
CN-1878830-B Conjugated diene rubber compositions, process for production of the same and products of crosslinking thereof ZEON CORP 2012-07-04 CN disclosed
CN-101679571-B Conjugated diene copolymer rubber, process for producing the same, rubber composition, and tire JSR CORP. (JP) 2012-02-01 CN disclosed
EP-1350814-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND METHOD OF CHANGING REFRACTIVE INDEX JSR Corporation (JP) 2003-10-08 EP disclosed