SCHEMBL275159

SCHEMBL275159

c1ccc(O[SiH](Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.50
TSHR P16473 1/20 0.50
CA4 P22748 1/20 0.45
KCNA3 P22001 1/20 0.41
CA5A P35218 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
NR1H2 P55055 1/20 0.38
BAX Q07812 1/20 0.38
MAOA P21397 1/20 0.38
ALDH1A1 P00352 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
RECQL P46063 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SRC P12931 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AKT1 P31749 1/20 0.35
AKT2 P31751 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058914 0.83 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2115686 0.83 CA4 (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL7698665 0.83 LTA4H (0.41) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL7694976 0.81 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1867149 0.81 TRPA1 (0.57) MAOAALDH1A1MAOB
SCHEMBL4427583 0.79 CA4 (0.46) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1609017 0.77 LTA4H (0.43) LTA4HTSHRCA4KCNA3L3MBTL1
SCHEMBL2114550 0.77 LTA4H (0.43) LTA4HTSHRCA4KCNA3L3MBTL1
SCHEMBL1609542 0.77 CA4 (0.39) LTA4HTSHRCA4KCNA3MAOA
SCHEMBL9816758 0.75 LTA4H (0.35) LTA4HTSHRCA4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118253348-A Carbonylation catalyst, preparation method and application thereof 万华化学集团股份有限公司 2024-06-28 CN claimed
CN-118126626-A Anti-crystallization super-slip coating for tunnel drainage system, preparation method and application 长安大学 2024-06-04 CN claimed
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
CN-112745210-B Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2022-02-15 CN claimed
CN-112745210-A Method for preparing alpha, beta-unsaturated carboxylic acid compound 中国科学院大连化学物理研究所 2021-05-04 CN claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
CN-112285872-A Laser mirror unit adjustment method applied to 1064nm 中国航空工业集团公司洛阳电光设备研究所 2021-01-29 CN claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
EP-3019510-B1 USE OF IMMOBILIZED MOLYBDEN- UND TUNGSTEN-CONTAINING CATALYSTS IN OLEFIN CROSS METATHESIS VERBIO VER BIOENERGIE AG (DE) 2020-12-02 EP claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof MITSUBISHI PHARMA CORPORATION (JP) 2007-07-12 US claimed
EP-1719764-A1 METHOD OF ASYMMETRICALLY REDUCING 4- 5-(IMIDAZOL-1-YL)-2-MET HYLBENZOYL -3,5-DIMETHYL-BENZOIC ACID OR ESTER THEREOF Mitsubishi Pharma Corporation (JP) 2006-11-08 EP claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
EP-0594175-B1 Process for producing aromatic polycarbonate MITSUBISHI CHEM CORP (JP) 1997-06-18 EP claimed
US-5391691-A Melt condensing am aromatic diol compound and a carbonic acid diester in the presence of an interesterification catalyst and co-presence of an organosilicon compound MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1995-02-21 US claimed
EP-0594175-A1 Process for producing aromatic polycarbonate MITSUBISHI CHEMICAL CORPORATION (JP) 1994-04-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 LTA4H 147/4885TSHR 4680/4885CA4 2135/4885
US-20070161803-A1 Method of asymmetrically reducing 4-[5-(imidazol-1-yl)-2-methylbenzoyl]-3,5- dimethylbenzoic acid or ester thereof DDC, AADAC, ALG3 LTA4H 736/4885TSHR 4742/4885CA4 803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.