SCHEMBL6948703

SCHEMBL6948703

COc1ccc(C=CC(=O)OC2CC(C)(C)N(C)C(C)(C)C2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.60
F3 P13726 2/20 0.50
THRB P10828 1/20 0.49
ATM Q13315 1/20 0.49
MAPK1 P28482 1/20 0.48
MAPT P10636 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GSK3B P49841 2/20 0.48
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
LMNA P02545 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 3/20 0.45
BACE1 P56817 1/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9211985 1.00 HTT (0.60) HTTF3THRBATMMAPK1
SCHEMBL6948701 1.00 HTT (0.60) HTTF3THRBATMMAPK1
SCHEMBL12590207 0.90 HTT (0.60) HTTF3THRBATMMAPK1
SCHEMBL12888653 0.89 HTT (0.56) HTTF3THRBATMMAPK1
SCHEMBL9211598 0.85 LMNA (0.53) HTTF3THRBATMMAPK1
SCHEMBL9211591 0.85 LMNA (0.53) HTTF3THRBATMMAPK1
SCHEMBL9207159 0.83 HTT (0.55) HTTF3THRBATMMAPT
SCHEMBL9207163 0.83 HTT (0.55) HTTF3THRBATMMAPT
SCHEMBL15961134 0.83 HTT (0.42) HTTF3THRBATMMAPK1
SCHEMBL78186 0.81 HTT (0.40) HTTF3MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174839-A1 STABILIZER MIXTURE BASF SE (DE) 2024-05-30 US claimed
EP-0517103-B1 Piperidine derivatives, a process for the preparation thereof and the use thereof 3V SIGMA SPA (IT) 1995-03-01 EP claimed
EP-0517103-A1 Piperidine derivatives, a process for the preparation thereof and the use thereof 3V SIGMA S.p.A (IT) 1992-12-09 EP claimed
WO-2023227472-A1 POLYCARBONATE COMPOSITION CONTAINING COMBINATION OF HYDROXYPHENYL TRIAZINES AND UV ABSORBERS BASF SE (DE) 2023-11-30 WO disclosed
CN-115175958-A Polyolefin compositions 巴斯夫欧洲公司 2022-10-11 CN disclosed
CN-114945458-A Method for producing an article with foam particles 耐克创新有限合伙公司 2022-08-26 CN disclosed
CN-114727684-A Method of manufacturing an article using foam particles 耐克创新有限合伙公司 2022-07-08 CN disclosed
CN-113100541-B Textile and article and process for manufacturing textile and article 耐克创新有限合伙公司 2022-06-14 CN disclosed
CN-110678510-B Nucleating agents, methods of making the same and related polymer compositions 巴斯夫欧洲公司 2022-03-29 CN disclosed
CN-114145542-A Textile and article and process for manufacturing textile and article 耐克创新有限合伙公司 2022-03-08 CN disclosed
CN-114073355-A Method for manufacturing articles using foam particles 耐克创新有限合伙公司 2022-02-22 CN disclosed
CN-111902477-A Use of ultraviolet radiation absorbing polymer composition (UVRAP) as UV absorber in coatings for non-biological and non-keratin materials 巴斯夫欧洲公司 2020-11-06 CN disclosed
CN-111051418-A Additive mixture 巴斯夫欧洲公司 2020-04-21 CN disclosed
CN-110809600-A Polyethylene pipe 巴斯夫欧洲公司 2020-02-18 CN disclosed
CN-110678510-A Nucleating agents, methods of making the same and related polymer compositions 巴斯夫欧洲公司 2020-01-10 CN disclosed
CN-110678097-A Method for manufacturing articles using foam particles 耐克创新有限合伙公司 2020-01-10 CN disclosed
CN-105636954-B Triazine, piperidine and pyrrolidinyl hindered amine light stabilizers 巴斯夫欧洲公司 2019-12-13 CN disclosed
EP-1319643-A2 Macromolecular HALS with a definite molecular weight 3V SIGMA S.p.A (IT) 2003-06-18 EP disclosed
EP-1276802-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS Great Lakes Chemical (Europe) GmbH (CH) 2003-01-22 EP disclosed
WO-2001081458-A1 LIQUID STABILIZING MIXTURES FOR ORGANIC POLYMERS GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 2001-11-01 WO disclosed