SCHEMBL6948768

SCHEMBL6948768

CCCCCn1nc(C(=O)O)c2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 7/20 0.61
CNR2 P34972 8/20 0.60
TSHR P16473 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
PMP22 Q01453 1/20 0.50
HIF1A Q16665 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KDM4E B2RXH2 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PKM P14618 1/20 0.48
CDC25A P30304 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30497875 1.00 CNR1 (0.61) CNR1CNR2TSHRCYP1A2CYP3A4
SCHEMBL2818345 0.96 CNR1 (0.60) CNR1CNR2TSHRCYP1A2CYP3A4
SCHEMBL9342889 0.91 CNR2 (0.58) CNR1CNR2TSHRKDM4EHSD17B10
SCHEMBL3017718 0.90 TSHR (0.53) CNR1CNR2TSHRCYP1A2CYP3A4
SCHEMBL15897843 0.88 PKM (0.52) CNR1CNR2TSHRCYP1A2CYP3A4
SCHEMBL6948881 0.87 CNR2 (0.61) CNR1CNR2TSHRKDM4EHSD17B10
SCHEMBL8874913 0.87 CNR1 (0.66) CNR1CNR2TSHRKDM4EHSD17B10
SCHEMBL24221989 0.86 CNR1 (0.65) CNR1CNR2CDC25A
SCHEMBL28985446 0.86 TSHR (0.50) CNR1CNR2TSHRCYP1A2CYP3A4
SCHEMBL15897842 0.85 PKM (0.55) CNR1CNR2TSHRCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC (CA) 2023-08-31 US disclosed
WO-2022006498-A1 METHOD OF TREATING CORONAVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC. (CA) 2022-01-06 WO disclosed
US-20210038559-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS PASCAL BIOSCIENCES INC. (CA) 2021-02-11 US disclosed
US-10591497-B2 Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family RANDOX LABORATORIES LTD. (GB) 2020-03-17 US disclosed
US-10591497-B2 Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family RANDOX LABORATORIES LTD. (GB) 2020-03-17 US disclosed
EP-2950103-B1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY RANDOX LABORATORIES LTD (GB) 2018-10-17 EP disclosed
US-20150346227-A1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY NORTHERN BANK LIMITED (IE) 2015-12-03 US disclosed
US-20150346227-A1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY NORTHERN BANK LIMITED (IE) 2015-12-03 US disclosed
EP-2950103-A1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY Randox Laboratories Ltd. (GB) 2015-12-02 EP disclosed
EP-2950103-A1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE 3-ADAMANTANYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY Randox Laboratories Ltd. (GB) 2015-12-02 EP disclosed
WO-2014167530-A1 CANNABINOID COMPOUNDS BOWDEN MATTHEW JAMES (NZ) 2014-10-16 WO disclosed
EP-0829474-B1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN SEIFUN GROUP INC (JP) 2003-04-09 EP disclosed
US-6096746-A Indazole compound containing a monocyclic amine structure NISSHIN FLOUR MILLING CO., LTD. (JP) 2000-08-01 US disclosed
US-5945434-A TREATMENT OF GASTROINTESTINAL DISORDERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-08-31 US disclosed
EP-0708105-B1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO (JP) 1998-12-23 EP disclosed
EP-0829474-A1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN FLOUR MILLING CO., LTD. (JP) 1998-03-18 EP disclosed
US-5684003-A GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS NISSHIN FLOUR MILLING CO., LTD. (JP) 1997-11-04 US disclosed
EP-0708105-A1 5-HT4 receptor agonists NISSHIN FLOUR MILLING CO., LTD. (JP) 1996-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES CNR1, CNR2, SARS1 CNR1 1/4885CNR2 2/4885TSHR 3605/4885
US-20150346227-A1 IMMUNOASSAY FOR SYNTHETIC CANNABINOIDS OF THE ADAMANTYL INDAZOLE/INDOLE-3-CARBOXAMIDE FAMILY CNR2, CNR1, IDO1 CNR1 2/4885CNR2 1/4885TSHR 1266/4885
US-20210038559-A1 CANNABINOIDS AND DERIVATIVES FOR PROMOTING IMMUNOGENICITY OF TUMOR AND INFECTED CELLS CNR1, CNR2, CD74 CNR1 1/4885CNR2 2/4885TSHR 3699/4885
US-10591497-B2 Immunoassay for synthetic cannabinoids of the adamantyl indazole/indole-3-carboxamide family CNR2, CNR1, IDO1 CNR1 2/4885CNR2 1/4885TSHR 1266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.