SCHEMBL6948803

SCHEMBL6948803

OCCCCC[Na]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30966241 1.00
SCHEMBL4596167 1.00 LMNA (0.44)
SCHEMBL9195259 1.00 LMNA (0.44)
SCHEMBL9199598 1.00 LMNA (0.44)
SCHEMBL9202330 1.00 LMNA (0.44)
SCHEMBL1374256 0.96
Cetostearyl Alcohol SCHEMBL28773463 0.85 LMNA (0.72)
Sulfuric Acid SCHEMBL28070099 0.85 GPR84 (0.36)
SCHEMBL4303710 0.84
Hydrochloric Acid SCHEMBL31456718 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587800-B1 IMMUNOMODULATORY AZASPIRANES ANORMED INC (CA) 2003-04-02 EP disclosed
EP-0771199-A1 METHODS SMITHKLINE BEECHAM CORPORATION (US) 1997-05-07 EP disclosed
US-5591748-A Immunomodulatory azaspiranes SMITHKLINE BEECHAM CORPORATION (US) 1997-01-07 US disclosed
EP-0727993-A4 1996-10-02 EP disclosed
EP-0727993-A1 (NON DESCRIPTIVE)-A METHOD FOR DELAYING HIV INDIVIDUAL AIDS BY ADMINISTRATION OF SUBSTITUTED AZASPIRANE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1996-08-28 EP disclosed
WO-1996003123-A1 METHODS SMITHKLINE BEECHAM CORPORATION (US) 1996-02-08 WO disclosed
US-5486626-A AMINATION USEING PHTHALIMIDE WITH HYDROXY COMPOUND AND TREATMENT WITH AQUEOUS ACID HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-23 US disclosed
US-5455247-A Methods for the treatment of hyperlipidemia using azaspiranes SMITHKLINE BEECHAM CORPORATION (US) 1995-10-03 US disclosed
WO-1995003047-A1 HUMAN IMMUNODEFICIENCY VIRUS TREATMENTS SMITHKLINE BEECHAM CORPORATION (US) 1995-02-02 WO disclosed
WO-1995003046-A1 A METHOD OF INHIBITING THE PRODUCTION OF HIV SMITHKLINE BEECHAM CORPORATION (US) 1995-02-02 WO disclosed
WO-1993015735-A1 (NON DESCRIPTIVE)-A METHOD FOR DELAYING HIV INDIVIDUAL AIDS BY ADMINISTRATION OF SUBSTITUTED AZASPIRANE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1993-08-19 WO disclosed
WO-1993007871-A1 METHODS FOR THE TREATMENT OF HYPERLIPIDEMIA USING AZASPIRANES SMITHKLINE BEECHAM CORPORATION (US) 1993-04-29 WO disclosed
WO-1992022294-A1 IMMUNOMODULATORY AZASPIRANES SMITHKLINE BEECHAM CORPORATION (US) 1992-12-23 WO disclosed
US-5017582-A Analgesics SANDOZ LTD. (CH) 1991-05-21 US disclosed
US-4910207-A Antipsychotic agent NOVARTIS AG (CH) 1990-03-20 US disclosed
US-4803199-A SEROTONIN ANTAGONIST, ANALGESIC ANTIARRHYTHMIC AGENTS NOVARTIS AG (CH) 1989-02-07 US disclosed
US-4798829-A 1-Azabicyclo[3,2,2]nonane derivatives having 5-HT receptor antagonist activity BEECHAM GROUP PLC. (GB) 1989-01-17 US disclosed
US-4797406-A MIGRAINES, ANTIARRHYTHMIA AGENTS SANDOZ LTD. (CH) 1989-01-10 US disclosed
US-4789673-A ANTISEROTONINE AGENTS NOVARTIS AG (CH) 1988-12-06 US disclosed
EP-0214772-A1 Novel compounds BEECHAM GROUP PLC (GB) 1987-03-18 EP disclosed