Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954155 | 0.91 | PPARG (0.43) | PPARGPPARAPPARDITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6944979 | 0.86 | PPARG (0.41) | PPARGPPARAPPARDLTA4HHPGD | |
| SCHEMBL7248494 | 0.86 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL7248373 | 0.81 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL6955086 | 0.80 | PPARG (0.36) | PPARGPPARAITGB3ITGA2B | |
| SCHEMBL6956385 | 0.80 | PPARG (0.42) | PPARGPPARAPPARD | |
| SCHEMBL6952576 | 0.79 | PPARG (0.45) | PPARGPPARAPPARD | |
| SCHEMBL6952568 | 0.78 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6948555 | 0.78 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL6955185 | 0.77 | LTA4H (0.37) | PPARGPPARALTA4HHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |