Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952404 | 0.88 | TNF (0.46) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6953586 | 0.87 | TNF (0.51) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6952900 | 0.84 | TNF (0.48) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6949189 | 0.79 | MAPK1 (0.57) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6955034 | 0.79 | NPC1 (0.54) | ALDH1A1NPC1RAB9AKMT2APPARA | |
| SCHEMBL6955185 | 0.75 | LTA4H (0.37) | ALDH1A1MEN1KMT2APPARAPPARG | |
| SCHEMBL6955076 | 0.74 | PPARA (0.54) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6948934 | 0.74 | MEN1 (0.45) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6952341 | 0.73 | MEN1 (0.44) | TNFALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL6957101 | 0.71 | L3MBTL1 (0.45) | ALDH1A1NPC1RAB9APPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |