Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477891 | 0.93 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL8481421 | 0.92 | MEN1 (0.52) | MEN1KMT2AALDH1A1LMNAADRB1 | |
| SCHEMBL8479732 | 0.92 | MEN1 (0.52) | MEN1KMT2AALDH1A1LMNAADRB1 | |
| SCHEMBL8479493 | 0.92 | MAPK1 (0.54) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL8109540 | 0.92 | MEN1 (0.52) | MEN1KMT2AALDH1A1LMNAADRB1 | |
| SCHEMBL8481607 | 0.90 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAHTR1A | |
| SCHEMBL8479423 | 0.89 | ADRB3 (0.53) | MEN1KMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8480926 | 0.89 | EPHX1 (0.51) | MEN1KMT2AALDH1A1GPR132MAPK1 | |
| SCHEMBL8482289 | 0.89 | MEN1 (0.49) | MEN1KMT2AALDH1A1LMNAADRB1 | |
| SCHEMBL7772042 | 0.88 | MEN1 (0.47) | MEN1KMT2AALDH1A1POLBADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1074544-B1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6388086-B1 | REACTING W 3-METHYLPYRIDINE WITH BASE; THEN EPOXY COMPOUND | KANEKA CORPORATION (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-1074544-A1 | Process for production of 3-(3-pyridyl)-1-propanol derivatives | KANEKA CORPORATION (JP) | 2001-02-07 | — | — | EP | disclosed |
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |