Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949056 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL27921610 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL27917108 | 0.98 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL8484330 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL28030840 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL28030272 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL7437113 | 0.84 | TSHR (0.59) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL19214788 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| Hydrochloric Acid SCHEMBL18989464 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1POLBLMNA | |
| SCHEMBL31109684 | 0.79 | TLR2 (0.47) | SMN1; SMN2RAB9ANPC1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0772771-B2 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2003-12-17 | — | — | EP | disclosed |
| EP-0772771-B1 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | DOW CHEMICAL CO (US) | 2000-03-15 | — | — | EP | disclosed |
| EP-0959352-A1 | Determining biodegradability of aspartic acid derivatives, degradable chelants, uses and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0772771-A1 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003644-A1 | DETERMINING BIODEGRADABILITY OF ASPARTIC ACID DERIVATIVES, DEGRADABLE CHELANTS, USES AND COMPOSITIONS THEREOF | THE DOW CHEMICAL COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |