Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27565961 | 0.99 | MAOA (0.55) | MAOANQO2HDAC4HDAC7HDAC5 | |
| Sulfuric Acid SCHEMBL6762068 | 0.95 | MAOA (0.52) | MAOANQO2HDAC4HDAC7HDAC5 | |
| SCHEMBL17187194 | 0.76 | HDAC4 (0.48) | MAOAHDAC4HDAC7HDAC5MEN1 | |
| Hydrochloric Acid SCHEMBL27565958 | 0.75 | HDAC4 (0.40) | MAOANQO2HDAC4HDAC7HDAC5 | |
| SCHEMBL2489236 | 0.72 | NQO2 (0.60) | MAOANQO2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7797017 | 0.72 | KMT2A (0.51) | MAOAHDAC4HDAC7HDAC5MEN1 | |
| SCHEMBL18682061 | 0.70 | CHRNB2 (0.57) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL6764552 | 0.69 | HDAC4 (0.36) | MAOANQO2HDAC4HDAC7HDAC5 | |
| SCHEMBL29539141 | 0.68 | NPC1 (0.58) | MAOAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL22321745 | 0.68 | NPC1 (0.58) | MAOAMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244650-B1 | ARYLAMINE DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA SA (FR) | 2003-06-25 | — | — | EP | disclosed |
| CN-1402722-A | Arylamine derivatives and their use as anti-telomerase agents | AVENTIS PHARMA SA (FR) | 2003-03-12 | — | — | CN | disclosed |
| EP-1244650-A1 | ARYLAMINE DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | Aventis Pharma S.A. (FR) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001040218-A1 | ARYLAMINE DERIVATIVES AND THEIR USE AS ANTI-TELOMERASE AGENT | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |