Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24947655 | 0.85 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL29558897 | 0.85 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL16844525 | 0.81 | DRD2 (0.32) | HTR2A | |
| SCHEMBL21625577 | 0.78 | HTR2A (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL16855179 | 0.78 | DRD2 (0.31) | HTR2A | |
| SCHEMBL6952377 | 0.77 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL789665 | 0.74 | HTR2A (0.32) | HTR2AHTR2CHTR2B | |
| SCHEMBL29558995 | 0.73 | CYP19A1 (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL24946530 | 0.73 | CYP19A1 (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL21625583 | 0.71 | HTR2A (0.37) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901483-B1 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| US-5981572-A | Benzofurans and benzopyrans as chronobiological agents | GLAXO WELLCOME INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0901483-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997043272-A2 | BENZOFURANS AND BENZOPYRANS AS CHRONOBIOLOGICAL AGENTS | GLAXO GROUP LIMITED (GB) | 1997-11-20 | — | — | WO | disclosed |