Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 18/20 | 0.74 |
| ▸ | MMP13 | P45452 | 17/20 | 0.74 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP14 | P50281 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945640 | 0.91 | MMP13 (0.61) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6950277 | 0.85 | MMP1 (0.66) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6950890 | 0.85 | MMP1 (1.00) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL7208089 | 0.82 | MMP1 (0.67) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL7209175 | 0.81 | MMP1 (0.89) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6967193 | 0.80 | MMP1 (0.66) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6953409 | 0.79 | MMP1 (0.86) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6954028 | 0.78 | MMP1 (0.69) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6965530 | 0.78 | MMP1 (0.67) | MMP1MMP13MMP2MMP9MMP14 | |
| SCHEMBL6957161 | 0.78 | MMP1 (0.67) | MMP1MMP13MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070058-B1 | (4-ARYLSULFONYLAMINO)-TETRAHYDROPYRAN-4-CARBOXYLIC ACID HYDROXAMIDES | PFIZER PROD INC (US) | 2003-05-02 | — | — | EP | claimed |