Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.64 |
| ▸ | DRD3 | P35462 | 9/20 | 0.64 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949383 | 1.00 | DRD2 (0.64) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL23045126 | 0.85 | DRD2 (0.50) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL23045120 | 0.85 | DRD2 (0.50) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL16233580 | 0.79 | DRD2 (0.66) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL1261038 | 0.79 | DRD2 (0.66) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6954655 | 0.78 | DRD2 (1.00) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6954646 | 0.78 | DRD2 (1.00) | DRD2DRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6957052 | 0.76 | DRD2 (0.96) | DRD2DRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL6957062 | 0.76 | DRD2 (0.96) | DRD2DRD3HTR1AHTR7 | |
| SCHEMBL6952511 | 0.74 | TRPV1 (0.36) | DRD2DRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757677-B1 | BENZOCYCLOHEXYLIMIDAZOLETHIONE DERIVATIVES | SYNTEX LLC (US) | 2003-06-18 | — | — | EP | disclosed |
| US-5719280-A | REACTING AMINE SUBSTITUTED BENZOCYCLOALKANE WITH DIALKYLOXYACETALDEHYDE IN PRESENCE OF REDUCING AGENT OR CATALYTIC HYDROGENATION, TREATING WITH THIOCYANIC ACID | SYNTEX (U.S.A.) INC. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0757677-A1 | BENZOCYCLOALKYLAZOLETHIONE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1997-02-12 | — | — | EP | disclosed |
| US-5538988-A | CARDIOVASCULAR DISORDERS AND DOPAMINE HYDROLASE ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. | 1996-07-23 | — | — | US | disclosed |
| WO-1995029165-A2 | BENZOCYCLOALKYLAZ0LETHIONE DERIVATIVES AS DOPAMIN BETA-HYDROXYLASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-11-02 | — | — | WO | disclosed |