Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992567 | 0.75 | ACHE (0.41) | BCHEACHECA12CA1CA2 | |
| SCHEMBL6947557 | 0.72 | HTR2A (0.36) | BCHEACHE | |
| SCHEMBL720558 | 0.71 | CYP1A2 (0.56) | RAB9AVDR | |
| SCHEMBL29955760 | 0.71 | CYP1A2 (0.56) | RAB9AVDR | |
| SCHEMBL17336725 | 0.71 | CYP3A4 (0.42) | — | |
| SCHEMBL6510805 | 0.68 | GPR84 (0.47) | — | |
| SCHEMBL7002379 | 0.68 | CYP2A6 (0.46) | ACHE | |
| SCHEMBL18733501 | 0.68 | CYP1A2 (0.46) | ACHE | |
| SCHEMBL11737832 | 0.68 | CYP1A2 (0.57) | BCHEACHERAB9ACA2 | |
| SCHEMBL31426083 | 0.68 | CYP2A6 (0.46) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509351-B1 | A method of inhibiting TNF- alpha in a patient in need thereof which comprises administering to said patient an effective amount of a compound for inflamation | SANOFI-SYNTELABO (FR) | 2003-01-21 | — | — | US | disclosed |