Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 4/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | MC1R | Q01726 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6199494 | 0.83 | MC4R (0.62) | MC4RMC3RMC1RDPP8DPP7 | |
| SCHEMBL6476840 | 0.81 | MC4R (0.60) | MC4RMC3RMC1RDPP8DPP7 | |
| SCHEMBL6477249 | 0.77 | MC4R (0.55) | MC4RMC3RMC1RDPP8DPP7 | |
| SCHEMBL6180972 | 0.70 | MC4R (0.43) | MC4ROPRD1MC3RMC1RALDH1A1 | |
| SCHEMBL6476091 | 0.66 | MC4R (0.70) | MC4RMC3RMC1RDPP8DPP7 | |
| SCHEMBL6476088 | 0.66 | MC4R (0.70) | MC4RMC3RMC1RDPP8DPP7 | |
| SCHEMBL13735733 | 0.64 | OPRM1 (0.47) | MC4ROPRD1HTTCACNA2D1CACNA1B | |
| SCHEMBL6476767 | 0.63 | MC4R (0.60) | MC4RMC3RMC1R | |
| SCHEMBL6476771 | 0.63 | MC4R (0.60) | MC4RMC3RMC1R | |
| Hydrochloric Acid SCHEMBL3403658 | 0.63 | OPRM1 (0.46) | MC4ROPRD1HTTCACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010010-A1 | Melanocortin receptor ligands | PROCTER & GAMBLE COMPANY, THE | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010010-A1 | Melanocortin receptor ligands | MC1R, MC4R, MC5R | MC4R 2/4885OPRD1 28/4885MC3R 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.