Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21002247 | 0.87 | ALOX15 (0.55) | MAPTPPARAKAT8ALDH1A1CYP1A2 | |
| SCHEMBL10935708 | 0.87 | MAPT (0.47) | RXFP1MAPTACHESGMS1SGMS2 | |
| SCHEMBL21034788 | 0.86 | ALOX15 (0.57) | MAPTPPARAALDH1A1LMNACYP1A2 | |
| SCHEMBL21034795 | 0.82 | ALOX15 (0.52) | MAPTALDH1A1LMNACYP1A2IGF1R | |
| SCHEMBL5692293 | 0.82 | CYP1A2 (0.50) | KAT8ALDH1A1LMNACYP1A2IGF1R | |
| SCHEMBL10067474 | 0.81 | PPARA (0.56) | PPARAACHEKAT8ALDH1A1LMNA | |
| SCHEMBL30342268 | 0.81 | PPARA (0.56) | PPARAACHEKAT8ALDH1A1LMNA | |
| SCHEMBL10824621 | 0.81 | IGF1R (0.68) | RXFP1MAPTACHESGMS1SGMS2 | |
| SCHEMBL10826793 | 0.81 | IGF1R (0.68) | RXFP1MAPTACHESGMS1SGMS2 | |
| SCHEMBL7162861 | 0.81 | F13A1 (0.51) | RXFP1MAPTLTB4RALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |