Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 10/20 | 0.52 |
| ▸ | IGF1R | P08069 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.48 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21034788 | 0.96 | ALOX15 (0.57) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL21002247 | 0.94 | ALOX15 (0.55) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL21034647 | 0.92 | ALDH1A1 (0.52) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL5166701 | 0.91 | NPC1 (0.56) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL10067474 | 0.88 | PPARA (0.56) | ALOX15IGF1RALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30342268 | 0.88 | PPARA (0.56) | ALOX15IGF1RALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5167973 | 0.86 | CNR1 (0.55) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL9246524 | 0.84 | ALOX15 (0.55) | ALOX15IGF1RALDH1A1MAPTKDM4E | |
| SCHEMBL21034774 | 0.83 | CA2 (0.54) | ALOX15ALDH1A1MAPTKDM4ECYP1A2 | |
| SCHEMBL6949592 | 0.82 | RXFP1 (0.50) | ALOX15IGF1RALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| US-20200375949-A1 | BISPHENOL COMPOUNDS | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-12-03 | — | — | US | disclosed |
| WO-2019104153-A1 | BISPHENOL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2019-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375949-A1 | BISPHENOL COMPOUNDS | RPP30, RPS10, RPS20 | ALOX15 2231/4885IGF1R 1859/4885ALDH1A1 1053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.