Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205807 | 0.84 | EPHX1 (0.40) | MMP3ADAM17EPHX1HPGDSMN1; SMN2 | |
| SCHEMBL27481273 | 0.84 | HSD17B10 (0.44) | EPHX1HPGDSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL18562140 | 0.81 | MMP3 (0.40) | MMP3ADAM17MEN1KMT2ACA1 | |
| SCHEMBL10201310 | 0.77 | HPGD (0.42) | EPHX1HPGDSMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL18565380 | 0.75 | CTSL (0.41) | MMP3ADAM17MEN1KMT2APREP | |
| SCHEMBL16611905 | 0.74 | CHRM2 (0.39) | EPHX1HPGDSMN1; SMN2HSD17B10PTPN2 | |
| SCHEMBL2848716 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HSD17B10LMNANPSR1 | |
| SCHEMBL15307926 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HSD17B10LMNANPSR1 | |
| SCHEMBL5403510 | 0.72 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1HSD17B10LMNANPSR1 | |
| SCHEMBL13140083 | 0.71 | TSHR (0.52) | SMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824544-B1 | PEPTIDYL COMPOUNDS WHICH INHIBIT METALLOPROTEINASE AND TNF LIBERATION AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LTD (GB) | 2003-04-16 | — | — | EP | disclosed |
| US-5994293-A | Peptidyl compounds and their therapeutic use | DARWIN DISCOVERY LTD. (GB) | 1999-11-30 | — | — | US | disclosed |