SCHEMBL6949892

SCHEMBL6949892

C=C/C(C)=C/OCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6949897 1.00
SCHEMBL27536826 0.75
SCHEMBL8677272 0.75 TSHR (0.39)
SCHEMBL2716472 0.74
SCHEMBL4767183 0.74
SCHEMBL751024 0.74
SCHEMBL23529565 0.72
SCHEMBL9717742 0.71 ALDH1A1 (0.39)
SCHEMBL11752475 0.71 ALDH1A1 (0.39)
SCHEMBL295231 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2799420-B1 METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE NANJING UNIVERSITY OF TECHNOLOGY (CN) 2016-11-16 EP claimed
US-9187394-B2 Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde NANJING UNIVERSITY OF TECHNOLOGY (CN) 2015-11-17 US claimed
EP-2799420-B1 METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE NANJING UNIVERSITY OF TECHNOLOGY (CN) 2016-11-16 EP disclosed
US-9187394-B2 Method for synthesizing 2,7-dimethyl-2,4,6-octatriene-1,8-dialdehyde NANJING UNIVERSITY OF TECHNOLOGY (CN) 2015-11-17 US disclosed
US-20140378711-A1 METHOD FOR SYNTHESIZING 2,7-DIMETHYL-2,4,6-OCTATRIENE-1,8-DIALDEHYDE NANJING UNIVERSITY OF TECHNOLOGY (CN) 2014-12-25 US disclosed
US-20110135600-A1 BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 2011-06-09 US disclosed
US-20110135600-A1 BICYCLIC TRAIZOLE DERIVATIVES FOR TREATING OF TUMORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 2011-06-09 US disclosed
EP-0931790-B1 Method for producing 2-sulfonylpyridine derivates and method for producing 2-( (2-pyridyl)methyl)thio)-1H-benzimidazole derivates KURARAY CO (JP) 2003-05-14 EP disclosed
EP-1004565-B1 Preparation of 1-alkoxy-2-methyl-1,3-butadienes HOFFMANN LA ROCHE (CH) 2002-10-23 EP disclosed
EP-0919547-B1 Preparation of polyenaldehydes HOFFMANN LA ROCHE (CH) 2002-06-05 EP disclosed
US-6350876-B2 REACTING SULFONYL CYANIDE DERIVATIVE WITH ALPHA,BETA-UNSAT-URATED CARBONYL COMPOUND; ORGANOLITHIUM COMPOUND; STARTING MATERIAL/INTERMEDIATE FOR DRUG SYNTHESIS (ANTI-PARKINSON'S DRUG LAZABEMIDE) AND AGRICULTURAL CHEMICALS (PESTICIDES) KURARAY CO., LTD. (JP) 2002-02-26 US disclosed
US-6018075-A BY REACTING GAMMA-BROMOTIGLIC ALDEHYDE OR GAMMA-CHLOROTIGLIC ALDEHYDE WITH SODIUM OR POTASSIUM ACETATE IN THE PRESENCE OF A PHASE TRANSFER CATALYST AND ORGANIC SOLVENT ROCHE VITAMINS INC. (US) 2000-01-25 US disclosed
US-5990360-A DEETHERIFICATION IN PRESENCE OF AN ALUMINIUM SILICATE CATALYST ROCHE VITAMINS INC. (US) 1999-11-23 US disclosed
EP-0931790-A2 Method for producing 2-sulfonylpyridine derivates and method for producing 2-( (2-pyridyl)methyl)thio)-1H-benzimidazole derivates KURARAY CO., LTD. (JP) 1999-07-28 EP disclosed
US-5929288-A A POLYENE O,O-DIALKYL ACETAL OR POLYENE DI(O,O-DIALKYL ACETAL) IS REACTED WITH A 1-ALKOXY-1,3-DIENE IN THE PRESENCE OF A LEWIS ACID OR A BRONSTED ACID. THE REACTION MIXTURE IS THEN HYDROLYZED AND THE ALCOHOL IS CLEAVED UNDER BASIC CONDITIONS. ROCHE VITAMINS INC. (US) 1999-07-27 US disclosed
EP-0919547-A1 Preparation of polyenaldehydes F. HOFFMANN-LA ROCHE AG (CH) 1999-06-02 EP disclosed
US-5786518-A HALOHYDROXYLATION OF ALKOXY-2-METHYL-1,3-BUTADIENE WITH ALKANOL AND HALOGEN THEN HYDROLYSIS ROCHE VITAMINS INC. (US) 1998-07-28 US disclosed
EP-0825168-A2 Preparation of gamma-halotiglinaldehydes F. HOFFMANN-LA ROCHE AG (CH) 1998-02-25 EP disclosed
EP-0816334-A1 Preparation of polyenic (di)aldehydes F. HOFFMANN-LA ROCHE AG (CH) 1998-01-07 EP disclosed
US-4105697-A Process for the preparation of α, β-ethylenic aldehydes RHONE-POULENC INDUSTRIES (FR) 1978-08-08 US disclosed