Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12536148 | 0.77 | KDM4E (0.72) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL5340573 | 0.76 | TNKS (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL2483048 | 0.76 | KDM4E (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL30503392 | 0.76 | KDM4E (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Acetic Acid SCHEMBL11510911 | 0.76 | KDM4E (0.53) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL19755648 | 0.74 | KDM4E (0.68) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL12325324 | 0.73 | KDM4E (0.66) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL7538814 | 0.73 | KDM4E (0.49) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL16915378 | 0.73 | HPGD (0.62) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL27625791 | 0.73 | MAPT (0.63) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140890-B1 | CHROMAN DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-26 | — | — | EP | disclosed |