Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.56 |
| ▸ | TNKS | O95271 | 8/20 | 0.53 |
| ▸ | PARP1 | P09874 | 6/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.53 |
| ▸ | GABRD | O14764 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503392 | 1.00 | KDM4E (0.56) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL15367852 | 0.81 | KDM4E (0.49) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL5340573 | 0.81 | TNKS (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL16915378 | 0.81 | HPGD (0.62) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| Acetic Acid SCHEMBL11510911 | 0.77 | KDM4E (0.53) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL11508591 | 0.77 | HPGD (0.51) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29382214 | 0.77 | TNKS (0.51) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL6949930 | 0.76 | KDM4E (0.55) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL1961365 | 0.76 | KDM4E (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B | |
| SCHEMBL29966031 | 0.76 | KDM4E (0.59) | KDM4EUSP2CSNK2A2PTGS1CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4326892-A1 | METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA | NAOS Institute of Life Science (FR) | 2024-02-28 | — | — | EP | claimed |
| WO-2022223928-A1 | METHOD FOR SELECTING ECOBIOLOGICAL TOPICAL COMPOSITIONS AND INGREDIENTS CAPABLE OF RESTORING OR REINFORCING THE SKIN MICROBIOTA | NAOS INSTITUTE OF LIFE SCIENCE (FR) | 2022-10-27 | — | — | WO | claimed |
| EP-3897867-A2 | COSMETIC COMPOSITIONS | Mary Kay, Inc. (US) | 2021-10-27 | — | — | EP | claimed |
| CN-106659915-B | Skin care compositions | 博姿有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112533493-A | Enzyme molecules that mimic antioxidant activity | 比奥尼克莱公司 | 2021-03-19 | — | — | CN | claimed |
| US-20200197472-A1 | COSMETIC COMPOSITIONS | MARY KAY INC. | 2020-06-25 | — | — | US | claimed |
| WO-2020131477-A2 | COSMETIC COMPOSITIONS | MARY KAY INC. (US) | 2020-06-25 | — | — | WO | claimed |
| EP-2706981-B1 | COSMETIC COMPOSITIONS | MARY KAY INC (US) | 2019-09-04 | — | — | EP | claimed |
| EP-2788010-B1 | SKIN CARE FORMULATION | MARY KAY INC (US) | 2018-10-24 | — | — | EP | claimed |
| CN-103987394-B | Skin care formulation | 玫琳凯有限公司 | 2018-05-11 | — | — | CN | claimed |
| CN-107961211-A | Cosmetic composition | 玫琳凯有限公司 | 2018-04-27 | — | — | CN | claimed |
| US-9526689-B2 | Skin care formulation | MARY KAY INC. (US) | 2016-12-27 | — | — | US | claimed |
| US-9233062-B2 | Cosmetic compositions | MARY KAY INC. (US) | 2016-01-12 | — | — | US | claimed |
| EP-2788010-A1 | SKIN CARE FORMULATION | Mary Kay, Inc. (US) | 2014-10-15 | — | — | EP | claimed |
| EP-2706981-A2 | COSMETIC COMPOSITIONS | MARY KAY INC. (US) | 2014-03-19 | — | — | EP | claimed |
| US-20130171283-A1 | SKIN CARE FORMULATION | MARY KAY INC. (US) | 2013-07-04 | — | — | US | claimed |
| WO-2013086518-A1 | SKIN CARE FORMULATION | MARY KAY INC. (US) | 2013-06-13 | — | — | WO | claimed |
| CN-103037838-A | cosmetic composition | MARY KAY INC | 2013-04-10 | — | — | CN | claimed |
| WO-2012154949-A2 | COSMETIC COMPOSITIONS | MARY KAY INC. (US) | 2012-11-15 | — | — | WO | claimed |
| US-20120288478-A1 | COSMETIC COMPOSITIONS | MARY KAY, INC. | 2012-11-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200197472-A1 | COSMETIC COMPOSITIONS | GLA, GUSB, MMP2 | KDM4E 802/4885USP2 2493/4885CSNK2A2 489/4885 |
| US-20120288478-A1 | COSMETIC COMPOSITIONS | HEXA, GLA, HEXB | KDM4E 1134/4885USP2 879/4885CSNK2A2 419/4885 |
| US-20130171283-A1 | SKIN CARE FORMULATION | CUTA, TYR, RAD50 | KDM4E 919/4885USP2 2351/4885CSNK2A2 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.