Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202807 | 0.90 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL6952030 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL294061 | 0.79 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL131249 | 0.79 | CA12 (0.57) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL109308 | 0.76 | ALDH1A1 (0.61) | ALDH1A1TSHRKMT2APLA2G1BATG4B | |
| SCHEMBL6948522 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL14767681 | 0.76 | CA12 (0.63) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL6954223 | 0.75 | CA12 (0.57) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL29387332 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTMEN1TP53 | |
| SCHEMBL42787 | 0.75 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |