Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946454 | 0.89 | TSHR (0.61) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL131249 | 0.84 | CA12 (0.57) | ALDH1A1LMNATSHRESR1CYP3A4 | |
| SCHEMBL130905 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL9197058 | 0.80 | TSHR (0.54) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL4722815 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL12984487 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL6950100 | 0.76 | ALDH1A1 (0.59) | ALDH1A1LMNATSHRTDP1CHRM1 | |
| SCHEMBL4721065 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL111664 | 0.74 | LMNA (0.75) | ALDH1A1LMNATSHRTDP1ESR1 | |
| SCHEMBL9196323 | 0.74 | CA12 (0.55) | ALDH1A1LMNATSHRESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0936218-B1 | BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6387938-B1 | Benzimidazole derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-14 | — | — | US | disclosed |
| EP-0936218-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |