Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6956676 | 0.90 | ACKR3 (0.54) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6955334 | 0.89 | ACKR3 (0.52) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6955022 | 0.79 | HDAC6 (0.51) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6952370 | 0.79 | PPARG (0.61) | ACKR3HDAC6PPARGPPARA | |
| SCHEMBL6953763 | 0.79 | NPC1 (0.55) | PPARGKDM4ETDP1ITGB1ITGA4 | |
| SCHEMBL6955376 | 0.79 | ACKR3 (0.49) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6956510 | 0.78 | HDAC6 (0.52) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6955832 | 0.77 | ACKR3 (0.55) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL6952836 | 0.77 | ACKR3 (0.50) | ACKR3HDAC6HDAC8PPARGKDM4E | |
| SCHEMBL8305576 | 0.76 | ACKR3 (0.49) | ACKR3HDAC6HDAC8PPARGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |