Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 6/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955022 | 0.83 | HDAC6 (0.51) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6955832 | 0.82 | ACKR3 (0.55) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6952836 | 0.82 | ACKR3 (0.50) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6957510 | 0.81 | MAPK1 (0.57) | NPC1GAASMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL6955334 | 0.80 | ACKR3 (0.52) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6956676 | 0.80 | ACKR3 (0.54) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6956510 | 0.80 | HDAC6 (0.52) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6952370 | 0.79 | PPARG (0.61) | ACKR3HDAC6PPARG | |
| SCHEMBL6955376 | 0.77 | ACKR3 (0.49) | ACKR3HDAC6KDM4EALOX15TSHR | |
| SCHEMBL6954585 | 0.76 | TNF (0.41) | KDM4EPPARGNPC1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |