Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | ACKR3 | P25106 | 6/20 | 0.51 |
| ▸ | PPARG | P37231 | 9/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955832 | 0.91 | ACKR3 (0.55) | HDAC6ACKR3PPARGPPARAKDM4E | |
| SCHEMBL6952836 | 0.85 | ACKR3 (0.50) | HDAC6ACKR3PPARGKDM4EALOX15 | |
| SCHEMBL6952370 | 0.83 | PPARG (0.61) | HDAC6ACKR3PPARGPPARAPPARD | |
| SCHEMBL6955334 | 0.83 | ACKR3 (0.52) | HDAC6ACKR3PPARGPPARAKDM4E | |
| SCHEMBL8305576 | 0.83 | ACKR3 (0.49) | HDAC6ACKR3PPARGKDM4EALOX15 | |
| SCHEMBL6955465 | 0.81 | MAPK1 (0.59) | — | |
| SCHEMBL6956510 | 0.81 | HDAC6 (0.52) | HDAC6ACKR3PPARGKDM4EALOX15 | |
| SCHEMBL6950203 | 0.79 | ACKR3 (0.50) | HDAC6ACKR3PPARGPPARAKDM4E | |
| SCHEMBL6956676 | 0.79 | ACKR3 (0.54) | HDAC6ACKR3PPARGPPARAKDM4E | |
| SCHEMBL6953483 | 0.79 | PPARG (0.60) | HDAC6ACKR3PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |