SCHEMBL6950221

Cc1cc(C(F)(F)F)c2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)O)c3Cl)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	RORC	P51449	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8028426	0.93	RORC (0.86)	RORC
SCHEMBL6946090	0.91	RORC (0.83)	RORC
SCHEMBL3743960	0.91	RORC (0.83)	RORC
SCHEMBL8521653	0.90	RORC (0.81)	RORC
SCHEMBL7009410	0.87	RORC (0.77)	RORC
SCHEMBL7013096	0.86	RORC (0.76)	RORC
SCHEMBL8182593	0.86	RORC (0.79)	RORC
SCHEMBL6942958	0.86	RORC (0.75)	RORC
SCHEMBL8442798	0.86	RORC (0.74)	RORC
SCHEMBL8183383	0.86	RORC (0.74)	RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0944618-B1	NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE	FOURNIER IND & SANTE (FR)	2003-09-24	—	—	EP	disclosed
US-6063791-A	N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use	FOURNIER INDUSTRIE ET SANTE (FR)	2000-05-16	—	—	US	disclosed
EP-0944618-A1	NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE	FOURNIER INDUSTRIE ET SANTE (FR)	1999-09-29	—	—	EP	disclosed
WO-1998024783-A1	NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE	FOURNIER INDUSTRIE ET SANTE (FR)	1998-06-11	—	—	WO	disclosed