Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3743960 | 1.00 | RORC (0.83) | RORCBDKRB2 | |
| SCHEMBL7952802 | 0.92 | RORC (0.72) | RORCBDKRB2 | |
| SCHEMBL8181772 | 0.92 | RORC (0.71) | RORCBDKRB2 | |
| SCHEMBL6950221 | 0.91 | RORC (1.00) | RORC | |
| SCHEMBL7811056 | 0.90 | RORC (0.70) | RORCBDKRB2 | |
| SCHEMBL7811053 | 0.90 | RORC (0.70) | RORCBDKRB2 | |
| Hydrochloric Acid SCHEMBL8041969 | 0.89 | BDKRB2 (0.74) | RORCBDKRB2 | |
| SCHEMBL6801276 | 0.88 | RORC (0.69) | RORCBDKRB2 | |
| SCHEMBL7812560 | 0.88 | RORC (0.72) | RORCBDKRB2 | |
| SCHEMBL6945138 | 0.88 | BDKRB2 (0.78) | RORCBDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944618-B1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER IND & SANTE (FR) | 2003-09-24 | — | — | EP | disclosed |
| EP-0874841-B1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| EP-0925295-B1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS B2 RECEPTOR ANTAGONISTS OF THE BRADYKININ | FOURNIER IND & SANTE (FR) | 2001-10-04 | — | — | EP | disclosed |
| US-6211181-B1 | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIALLERGENS, AND ANTIASTHMATICS | FOURNIER INDUSTRIE ET SANTE (FR) | 2001-04-03 | — | — | US | disclosed |
| US-6071917-A | ANALGESICS; ANTIINFLAMMATORY AGENTS; ESPECIALLY FOR THE TREATMENT OF ASTHMA, CEREBRAL TRAUMATIC SHOCK AND ALLERGIC RHINITIS; COMPETITIVE BINDING AT RECEPTORS | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-06-06 | — | — | US | disclosed |
| US-6063791-A | N-benzenesulfonyl-L-proline derivatives, method for preparing and therapeutic use | FOURNIER INDUSTRIE ET SANTE (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0944618-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-09-29 | — | — | EP | disclosed |
| EP-0925295-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-06-30 | — | — | EP | disclosed |
| EP-0874841-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR B2 ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998024783-A1 | NOVEL N-BENZENESULPHONYL-L-PROLINE DERIVATIVES, METHOD FOR PREPARING AND THERAPEUTIC USE | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-06-11 | — | — | WO | disclosed |
| WO-1998003503-A1 | N-BENZENESULPHONYL-L-PROLINE DERIVATIVES AS BRADYKININ B2 AGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1998-01-29 | — | — | WO | disclosed |
| WO-1997024349-A1 | 1-BENZENESULFONYL PYRROLIDINE DERIVATIVES AS BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-07-10 | — | — | WO | disclosed |