Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.60 |
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | PPARD | Q03181 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950369 | 0.92 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL6949208 | 0.90 | PPARA (0.56) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6947495 | 0.87 | PPARA (0.46) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6952339 | 0.84 | L3MBTL1 (0.46) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6949251 | 0.84 | L3MBTL1 (0.46) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6952340 | 0.82 | L3MBTL1 (0.47) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6956237 | 0.80 | PPARG (0.48) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6952264 | 0.80 | PPARG (0.48) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6954944 | 0.78 | PPARA (0.50) | PPARAPPARGPPARDL3MBTL1TDP1 | |
| SCHEMBL6955761 | 0.78 | L3MBTL1 (0.45) | PPARAPPARGPPARDL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |