Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954944 | 0.91 | PPARA (0.50) | PPARAL3MBTL1TDP1SMN1; SMN2PPARG | |
| SCHEMBL6950311 | 0.87 | PPARA (0.60) | PPARAL3MBTL1TDP1SMN1; SMN2PPARG | |
| SCHEMBL6950369 | 0.78 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL6949208 | 0.77 | PPARA (0.56) | PPARAL3MBTL1TDP1SMN1; SMN2PPARG | |
| SCHEMBL6953863 | 0.75 | KMT2A (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6953729 | 0.74 | HTR1A (0.40) | PPARAPPARGPPARDALDH1A1POLB | |
| SCHEMBL7532542 | 0.72 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL7852911 | 0.72 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL7535616 | 0.72 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6945353 | 0.71 | TNF (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |