SCHEMBL6950324

SCHEMBL6950324

CN1CCC(CCN2C(=O)c3ccccc3C2=O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 1.00
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476989 0.89 ACHE (0.81) ACHEKMT2A
SCHEMBL7407102 0.88 ACHE (0.78) ACHE
Methyl Alcohol SCHEMBL28751304 0.87 ACHE (0.77) ACHE
SCHEMBL27682918 0.86 ACHE (0.76) ACHE
SCHEMBL6957478 0.85 ACHE (0.74) ACHEKMT2A
SCHEMBL4245809 0.83 ACHE (0.71) ACHEKMT2A
SCHEMBL6947119 0.83 ACHE (0.70) ACHE
SCHEMBL6789650 0.82 ACHE (0.69) ACHE
SCHEMBL11710900 0.82 ACHE (0.69) ACHE
SCHEMBL27473165 0.81 ACHE (0.68) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0829474-B1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN SEIFUN GROUP INC (JP) 2003-04-09 EP disclosed
US-6096746-A Indazole compound containing a monocyclic amine structure NISSHIN FLOUR MILLING CO., LTD. (JP) 2000-08-01 US disclosed
US-5945434-A TREATMENT OF GASTROINTESTINAL DISORDERS NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-08-31 US disclosed
EP-0829474-A1 INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP NISSHIN FLOUR MILLING CO., LTD. (JP) 1998-03-18 EP disclosed