SCHEMBL6950375

SCHEMBL6950375

COc1cc(C(c2ccc(O)c(OC)c2)(C(F)(F)F)C(F)(F)F)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.52
TRIM24 O15164 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
ALDH5A1 P51649 1/20 0.49
ABAT P80404 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
TRIM33 Q9UPN9 1/20 0.49
TMEM97 Q5BJF2 1/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
CXCL12 P48061 1/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
DUSP3 P51452 1/20 0.45
TRPA1 O75762 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24928749 0.85 ALDH1A1 (0.49) ALDH1A1MEN1KMT2AESR1ESR2
SCHEMBL5356117 0.85 MAOB (0.52) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL15929636 0.85 ESR1 (0.44) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL365716 0.85 MAOB (0.55) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL16362169 0.83 MAOB (0.53) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL13695141 0.83 ESR1 (0.46) ESR1ESR2
SCHEMBL22209021 0.82 MAOB (0.53) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL125447 0.79 MAOB (0.57) MAOBTRIM24ALDH1A1HPGDALDH5A1
SCHEMBL9764127 0.79 PKM (0.44) HPGDKMT2AESR1ESR2CA2
SCHEMBL29445694 0.79 MAOB (0.57) MAOBTRIM24ALDH1A1HPGDALDH5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633497-B2 Methacrylic resin composition, molded article, film, and polarizing plate KURRAY CO., LTD. (JP) 2020-04-28 US disclosed
US-10196510-B2 Methacrylic resin composition and molded body thereof KURARAY CO., LTD. (JP) 2019-02-05 US disclosed
US-20170183463-A1 METHACRYLIC RESIN COMPOSITION, MOLDED ARTICLE, FILM, AND POLARIZING PLATE KURARAY CO., LTD. (JP) 2017-06-29 US disclosed
US-9605121-B2 Film KURARAY CO., LTD. (JP) 2017-03-28 US disclosed
US-20160096937-A1 FILM KURARAY CO., LTD. (JP) 2016-04-07 US disclosed
US-20160090479-A1 METHACRYLIC RESIN COMPOSITION AND MOLDED BODY THEREOF KURARAY CO., LTD. (JP) 2016-03-31 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
EP-0896975-B1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN CO (JP) 2003-06-04 EP disclosed
EP-1288242-A2 Polycarbonate, and molding and electrophotograpic photoreceptor prepared therefrom Idemitsu Kosan Co., Ltd. (JP) 2003-03-05 EP disclosed
US-6136521-A POLYORGANOSILOXANE-CONTAINING POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
EP-0896975-A1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1999-02-17 EP disclosed