Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 19/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19237285 | 0.77 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7134948 | 0.74 | SLC6A4 (0.66) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7134955 | 0.74 | SLC6A4 (0.66) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL10512624 | 0.73 | CYP19A1 (0.38) | — | |
| SCHEMBL6966843 | 0.72 | TACR1 (0.48) | — | |
| SCHEMBL22917998 | 0.71 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7768734 | 0.70 | SLC6A4 (0.56) | BACE1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20457210 | 0.69 | SLC6A4 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11810342 | 0.69 | SLC6A4 (0.40) | BACE1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7555128 | 0.69 | TACR1 (0.59) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791592-B1 | Azetidines | PFIZER LTD (GB) | 2003-05-21 | — | — | EP | disclosed |
| US-6022971-A | Azetidines | PFIZER INC (US) | 2000-02-08 | — | — | US | disclosed |
| US-5741790-A | Azetidines | PFIZER INC. (US) | 1998-04-21 | — | — | US | disclosed |
| EP-0791592-A2 | Azetidines | Pfizer Limited (GB) | 1997-08-27 | — | — | EP | disclosed |