Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 18/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7134955 | 0.92 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL7134948 | 0.92 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL20457222 | 0.79 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL6957461 | 0.79 | SLC6A4 (0.70) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL6994188 | 0.78 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL6970883 | 0.78 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL6990556 | 0.78 | SLC6A4 (0.84) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL6996236 | 0.77 | SLC6A2 (0.82) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL8568964 | 0.77 | SLC6A2 (0.82) | SLC6A4SLC6A2SLC6A3CYP2D6CYP1A2 | |
| SCHEMBL6950674 | 0.77 | BACE1 (0.45) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233333-A1 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE | EUTHYMICS BIOSCIENCE, INC. | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233333-A1 | PROCESS FOR THE SYNTHESIS OF (+) AND (-)-1-(3,4-DICHLOROPHENYL)-3-AZABICYCLO[3.1.0]HEXANE | ADH1C, DDT, UROD | SLC6A4 178/4885SLC6A2 185/4885SLC6A3 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.