Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955523 | 0.92 | PPARA (0.46) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6951283 | 0.79 | PPARA (0.54) | PPARAPPARGPPARDMAPTRXFP1 | |
| SCHEMBL6956426 | 0.77 | PPARG (0.59) | PPARAPPARGPPARDMEN1NPC1 | |
| SCHEMBL6955076 | 0.75 | PPARA (0.54) | PPARAPPARGPPARDRXFP1MEN1 | |
| SCHEMBL6949766 | 0.74 | PPARG (0.46) | PPARAPPARGPPARDGAAMAPT | |
| SCHEMBL6956161 | 0.70 | PPARG (0.46) | PPARAPPARGPPARDGAARXFP1 | |
| SCHEMBL6952391 | 0.70 | PPARG (0.46) | PPARAPPARGPPARDGAARXFP1 | |
| SCHEMBL8446636 | 0.70 | PPARG (0.38) | PPARAPPARGPPARD | |
| SCHEMBL6956263 | 0.70 | PPARG (0.45) | PPARAPPARGPPARDRAB9A | |
| SCHEMBL6955465 | 0.69 | MAPK1 (0.59) | GAAMAPTMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903343-B1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP CO LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0903343-A1 | Alpha-Substituted phenylpropionic acid derivative and medicine containing the same | SSP Co., Ltd. (JP) | 1999-03-24 | — | — | EP | disclosed |