SCHEMBL6955523

SCHEMBL6955523

COc1cc2c(=O)n(CCOc3ccc(CC(OC(C)C)C(=O)O)cc3)c(=O)n(C)c2cc1OC

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.46
PPARG P37231 18/20 0.46
PPARD Q03181 6/20 0.46
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6950697 0.92 PPARA (0.43) PPARAPPARGPPARDMAPT
SCHEMBL6956426 0.85 PPARG (0.59) PPARAPPARGPPARD
SCHEMBL6955076 0.76 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL6952327 0.73 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL6951283 0.70 PPARA (0.54) PPARAPPARGPPARDMAPT
SCHEMBL8306160 0.69 PPARG (0.46) PPARAPPARGPPARD
SCHEMBL4346276 0.68 PPARA (0.55) PPARAPPARGPPARD
SCHEMBL5727708 0.68 PPARG (0.60) PPARAPPARG
SCHEMBL5727704 0.68 PPARG (0.60) PPARAPPARG
SCHEMBL5727644 0.68 PPARG (0.73) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0903343-B1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP CO LTD (JP) 2003-05-28 EP disclosed
EP-0903343-A1 Alpha-Substituted phenylpropionic acid derivative and medicine containing the same SSP Co., Ltd. (JP) 1999-03-24 EP disclosed