Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CBR1 | P16152 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6945838 | 0.80 | MAOA (0.42) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL5079030 | 0.79 | ANTXR2 (0.71) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL6345040 | 0.75 | MAOA (0.46) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL6945650 | 0.75 | MEN1 (0.48) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL9467855 | 0.75 | MAOA (0.46) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL29361626 | 0.75 | MAOA (0.46) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL31086523 | 0.74 | MAOA (0.45) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL6946660 | 0.74 | MAOA (0.45) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL3191297 | 0.72 | MEN1 (0.45) | MAOAANTXR2MEN1KMT2ASLC22A2 | |
| SCHEMBL6352501 | 0.72 | RECQL (0.45) | MAOAANTXR2MEN1KMT2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930310-B1 | ISOCOUMARIN DERIVATIVES AND USE THEREOF IN DRUGS | MERCIAN CORP (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-6020363-A | IMMUNOLOGY MODERATORS, ANTICANCER AGENTS | MERCIAN CORPORATION (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0930310-A1 | ISOCOUMARIN DERIVATIVES AND USE THEREOF IN DRUGS | MERCIAN CORPORATION (JP) | 1999-07-21 | — | — | EP | disclosed |