Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923451 | 0.77 | TDP1 (0.39) | TSHRTDP1 | |
| SCHEMBL201992 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL11074667 | 0.75 | TDP1 (0.50) | TSHRTDP1LMNA | |
| SCHEMBL15764292 | 0.74 | — | — | |
| SCHEMBL10823298 | 0.74 | TSHR (0.37) | TSHRTDP1LMNA | |
| SCHEMBL11654598 | 0.73 | TDP1 (0.39) | TSHRTDP1LMNA | |
| SCHEMBL13451653 | 0.72 | TDP1 (0.35) | TDP1 | |
| SCHEMBL15764293 | 0.72 | — | — | |
| SCHEMBL15764702 | 0.72 | — | — | |
| SCHEMBL8357677 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |