Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206579 | 0.80 | USP2 (0.44) | TDP1USP2 | |
| SCHEMBL135974 | 0.79 | — | — | |
| SCHEMBL12020546 | 0.79 | — | — | |
| SCHEMBL11074667 | 0.77 | TDP1 (0.50) | TDP1HSD17B10MAPT | |
| SCHEMBL55052 | 0.75 | — | — | |
| SCHEMBL11654598 | 0.75 | TDP1 (0.39) | TDP1HSD17B10 | |
| SCHEMBL8865513 | 0.75 | — | — | |
| SCHEMBL15923451 | 0.74 | TDP1 (0.39) | TDP1HSD17B10 | |
| SCHEMBL106780 | 0.74 | — | — | |
| SCHEMBL20295231 | 0.73 | HSD17B10 (0.34) | HSD17B10MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351973-B1 | CONJUGATES OF IMMUNE CELL SPECIFIC MACROLIDE COMPOUNDS WITH ANTI-INFLAMMATORY COMPOUNDS FOR IMPROVED CELLULAR TARGETING OF ANTI-INFLAMMATORY THERAPY | GLAXOSMITHKLINE ZAGREB (HR) | 2010-03-31 | — | — | EP | disclosed |