Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6952970 | 0.99 | KDM4E (0.53) | HSD17B10KDM4EGAAL3MBTL1MEN1 | |
| SCHEMBL6953804 | 0.93 | CNR1 (0.56) | HSD17B10KDM4EGAAL3MBTL1MEN1 | |
| SCHEMBL6955741 | 0.91 | MEN1 (0.53) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7393720 | 0.89 | KDM4E (0.53) | HSD17B10KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL6955313 | 0.89 | SMN1; SMN2 (0.51) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6948551 | 0.88 | CNR1 (0.53) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7394157 | 0.88 | KDM4E (0.55) | HSD17B10KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL6950281 | 0.87 | CNR1 (0.56) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7394611 | 0.86 | KMT2A (0.64) | HSD17B10KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6950861 | 0.85 | KDM4E (0.49) | HSD17B10KDM4EGAAL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0829474-B1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN SEIFUN GROUP INC (JP) | 2003-04-09 | — | — | EP | disclosed |
| EP-0732333-B1 | Indazolecarboxamides | LILLY CO ELI (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6096746-A | Indazole compound containing a monocyclic amine structure | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5945434-A | TREATMENT OF GASTROINTESTINAL DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| US-5817676-A | 5-HT4 RECEPTOR ANTAGONISTS, CARDIOVASCULAR DISORDERS | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5798367-A | ANTAGONIZE 5-HYDROXYTRYPTAMINE RECEPTOR IN GASTROINTESTINAL TRACT OR GENITOURINARY TRACT | ELI LILLY AND COMPANY (US) | 1998-08-25 | — | — | US | disclosed |
| EP-0829474-A1 | INDAZOLE DERIVATIVES HAVING MONOCYCLIC AMINO GROUP | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5654320-A | SEROTONIN RECEPTOR ANTAGONIST | ELI LILLY AND COMPANY (US) | 1997-08-05 | — | — | US | disclosed |
| WO-1996033713-A1 | INDAZOLECARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1996-10-31 | — | — | WO | disclosed |
| EP-0732333-A1 | Indazolecarboxamides | ELI LILLY AND COMPANY (US) | 1996-09-18 | — | — | EP | disclosed |