Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951483 | 0.93 | GPR119 (0.53) | GPR119MEN1KMT2AALKF10 | |
| SCHEMBL6948395 | 0.93 | GPR119 (0.51) | GPR119MEN1KMT2AALKF10 | |
| SCHEMBL6960654 | 0.93 | GPR119 (0.53) | GPR119ALKF10F2KCNH2 | |
| SCHEMBL6951897 | 0.92 | GPR119 (0.50) | GPR119ALKF10F2KCNH2 | |
| SCHEMBL6948410 | 0.90 | GPR119 (0.58) | GPR119ALKF10F2PTPRB | |
| SCHEMBL6956441 | 0.90 | GPR119 (0.51) | GPR119MEN1KMT2AALKF10 | |
| SCHEMBL6955819 | 0.89 | GPR119 (0.51) | GPR119ALKF10F2PTPRB | |
| SCHEMBL6952182 | 0.89 | GPR119 (0.51) | GPR119ALKF10PTPRBPTPN11 | |
| SCHEMBL6959472 | 0.89 | GPR119 (0.51) | GPR119MEN1KMT2AALKF10 | |
| SCHEMBL6959665 | 0.89 | GPR119 (0.52) | GPR119MEN1KMT2AALKF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |