Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477005 | 0.92 | GPR119 (0.48) | GPR119ALKPDE4APDE4BPDE4C | |
| SCHEMBL6956441 | 0.91 | GPR119 (0.51) | GPR119ALKPTPRBPTPN11F10 | |
| SCHEMBL6955819 | 0.90 | GPR119 (0.51) | GPR119ALKPTPRBPTPN11F10 | |
| SCHEMBL6951070 | 0.89 | GPR119 (0.54) | GPR119ALKPTPRBPTPN11F10 | |
| SCHEMBL6951483 | 0.89 | GPR119 (0.53) | GPR119ALKPDE4APDE4BPDE4C | |
| SCHEMBL6948395 | 0.88 | GPR119 (0.51) | GPR119ALKF10KCNH2MEN1 | |
| SCHEMBL6948410 | 0.87 | GPR119 (0.58) | GPR119ALKPTPRBPTPN11F10 | |
| SCHEMBL8480357 | 0.86 | GPR119 (0.49) | GPR119ALKPTPRBPTPN11MEN1 | |
| SCHEMBL6952182 | 0.86 | GPR119 (0.51) | GPR119ALKPTPRBPTPN11F10 | |
| SCHEMBL6959665 | 0.86 | GPR119 (0.52) | GPR119ALKPTPRBPTPN11F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798295-B1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-5869501-A | PREVENTION AND/OR TREATMENT OF DISEASES CAUSED BY THROMBUS OR EMBOLUS. | YAMANOUCHI PHARMACEUTICAL CO. LTD (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0798295-A1 | NOVEL AMIDINONAPHTHYL DERIVATIVE OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |