Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416230 | 0.93 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL7478756 | 0.93 | KDM4E (0.68) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL9353406 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL9581133 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL9685003 | 0.83 | CYP19A1 (0.54) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL14142602 | 0.82 | ALDH1A1 (0.78) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL9353451 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL6944584 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL7483463 | 0.77 | KDM4E (0.52) | ALDH1A1KDM4EPOLBHPGDNPC1 | |
| SCHEMBL23665263 | 0.77 | GRIK2 (0.72) | ALDH1A1KDM4EPOLBHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6345760-A | — | — | None | — | — | JP | disclosed |
| EP-0581589-B1 | Phthalide compounds, and recording materials using the compounds | YAMAMOTO CHEMICALS INC (JP) | 2003-03-26 | — | — | EP | disclosed |
| JP-H06345760-A | PHTHALIDE COMPOUND AND RECORDING MATERIAL | YAMAMOTO CHEM INC | 1994-12-20 | — | — | JP | disclosed |
| EP-0581589-A2 | Phthalide compounds, and recording materials using the compounds | YAMAMOTO CHEMICALS, INC. (JP) | 1994-02-02 | — | — | EP | disclosed |
| US-5229522-A | Reaction of indole and acetic anhydride with Lewis acids as catalysts | APPLETON PAPERS INC. (US) | 1993-07-20 | — | — | US | disclosed |
| US-5118814-A | Pressure sensitive and heat sensitive recording media | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-5001105-A | Bis-(indoly)ethylenes record systems utilizing such compounds | APPLETON PAPERS INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-4996328-A | Chromogens | APPLETON PAPERS INC. (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0386992-A2 | Colour formers for recording sheets | APPLETON PAPERS INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| EP-0370198-A1 | Tetraindolyl heptamethine derivatives | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |