Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957772 | 0.83 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6043904 | 0.81 | SLC6A3 (0.49) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6041607 | 0.76 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6960210 | 0.71 | SLC6A3 (0.47) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6952186 | 0.70 | SLC6A3 (0.40) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL9243087 | 0.70 | SLC6A3 (0.54) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL6958295 | 0.69 | KDM4E (0.46) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7282832 | 0.69 | SLC6A3 (0.75) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL13752150 | 0.69 | SLC6A3 (0.75) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7289188 | 0.69 | SLC6A3 (0.75) | SLC6A3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |