Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957772 | 0.89 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6958295 | 0.87 | KDM4E (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6041887 | 0.73 | SLC6A3 (0.62) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6041777 | 0.73 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL6954303 | 0.72 | MEN1 (0.38) | SLC6A3SLC6A2SLC6A4KDM1A | |
| SCHEMBL6952802 | 0.71 | SLC6A3 (0.50) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL29691862 | 0.68 | RORC (0.42) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL29691792 | 0.67 | RORC (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL440565 | 0.67 | SLC6A4 (0.45) | SLC6A3SLC6A2SLC6A4KDM1A | |
| SCHEMBL15314508 | 0.67 | SLC6A4 (0.45) | SLC6A3SLC6A2SLC6A4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |