SCHEMBL75556

SCHEMBL75556

OCCOCC(COCCO)(COCCO)COCCO

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.56
MAPK1 P28482 1/20 0.56
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
ALDH1A1 P00352 1/20 0.45
THRB P10828 2/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14997582 0.97 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL14997583 0.97 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL7898330 0.94 MEN1 (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL11954753 0.94 MEN1 (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL26397994 0.94 MEN1 (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL26474467 0.91 MEN1 (0.61) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL15463146 0.88 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL3841379 0.88 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL25885638 0.88 TSHR (0.50) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL24052896 0.87 MEN1 (0.55) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3707193-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF The Johns Hopkins University (US) 2020-09-16 EP claimed
US-20190142964-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF Ashvattha Therapeutics, Inc. 2019-05-16 US claimed
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY UNIV JOHNS HOPKINS (US) 2026-04-16 US disclosed
US-20250352653-A1 NEURON TARGETED 2-DEOXYGLUCOSE DENDRIMER FOR IMAGING AND TREATMENT OF NEUROLOGICAL DISEASES UNIV WASHINGTON STATE (US) 2025-11-20 US disclosed
US-20250269044-A1 PSMA-TARGETED DENDRIMER NANOPLATFORM FOR CANCER DETECTION AND THERAPY WASHINGTON STATE UNIVERSITY 2025-08-28 US disclosed
EP-4577246-A1 DENDRIMER CONJUGATES OF ANTIDEPRESSANT AND ANTIPSYCHOTIC AGENTS AND THEIR METHODS OF USE The Johns Hopkins University (US) 2025-07-02 EP disclosed
EP-4577245-A1 DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF PSYCHEDELIC THERAPEUTICS The Johns Hopkins University (US) 2025-07-02 EP disclosed
EP-4577247-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY The Johns Hopkins University (US) 2025-07-02 EP disclosed
WO-2025137151-A2 DENDRIMER COMPOSITIONS FOR THE TREATMENT OF ATHEROSCLEROSIS, OBESITY, AND METABOLIC SYNDROMES THE JOHNS HOPKINS UNIVERSITY (US) 2025-06-26 WO disclosed
US-20250195672-A1 DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF THERAPEUTICS TO NEURONS THE JOHNS HOPKINS UNIVERSITY 2025-06-19 US disclosed
EP-4504268-A1 DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF THERAPEUTICS TO NEURONS The Johns Hopkins University (US) 2025-02-12 EP disclosed
US-20080290034-A1 Bridged macrocyclic module compositions COVALENT PARTNERS LLC 2008-11-27 US disclosed
US-20080290034-A1 Bridged macrocyclic module compositions COVALENT PARTNERS LLC 2008-11-27 US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 US disclosed
US-7368564-B2 Bridged macrocyclic module compositions COVALENT PARTNERS, LLC (US) 2008-05-06 US disclosed
US-20080039547-A1 Moisture activated latent curing adhesive or sealant ETHICON, INC. 2008-02-14 US disclosed
US-20080039548-A1 Moisture activated latent curing adhesive or sealant ETHICON, INC. 2008-02-14 US disclosed
US-20070293569-A1 Pentaerythritol Derivatives and a Method for Preparation Thereof, and Liquid Crystal Base Containing the Same AMOREPACIFIC CORPORATION 2007-12-20 US disclosed
US-20070059563-A1 Magnetic recording medium FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070059563-A1 Magnetic recording medium FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080039548-A1 Moisture activated latent curing adhesive or sealant ICAM1, EHMT1, CDH1 TSHR 4861/4885MAPK1 2967/4885MEN1 1948/4885
US-20070293569-A1 Pentaerythritol Derivatives and a Method for Preparation Thereof, and Liquid Crystal Base Containing the Same ELOVL1, SQLE, MSMO1 TSHR 4366/4885MAPK1 1100/4885MEN1 1180/4885
US-20250195672-A1 DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY OF THERAPEUTICS TO NEURONS GPR119, SLC2A2, SLC2A1 TSHR 1397/4885MAPK1 2708/4885MEN1 513/4885
US-20190142964-A1 DENDRIMER DELIVERY SYSTEM AND METHODS OF USE THEREOF TLR3, CD40LG, OXGR1 TSHR 2190/4885MAPK1 2303/4885MEN1 3686/4885
US-20260102502-A1 CANNABINOID DENDRIMER COMPOSITIONS FOR TARGETED DELIVERY CNR1, CNR2, GPR18 TSHR 1425/4885MAPK1 2475/4885MEN1 4032/4885
US-20080039547-A1 Moisture activated latent curing adhesive or sealant ICAM1, EHMT1, CDH1 TSHR 4861/4885MAPK1 2967/4885MEN1 1948/4885
US-20080290034-A1 Bridged macrocyclic module compositions SBDS, NCL, INTS6 TSHR 4746/4885MAPK1 3815/4885MEN1 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.